Orally disintegrating tablet: A review

نویسندگان

چکیده

Orally dispersive tablets are solid dosage forms that dissolve in the mouth within 10 to 30 seconds, enabling waterless ingestion. The tablet dissolves quickly due its fast breakdown, which also causes effects start acting quickly. ODTs can help patients with a variety of conditions, including pediatrics, geriatrics, psychosis, dysphagia, bedridden discomfort, comatose patients, young undeveloped muscular and nervous systems, hand tremors, who travel often. It provides high stability, precise dosage, efficient manufacture, smaller packing; self-administration is allowed on long journeys because water not required. cost-effective way distribute drugs. When medicine absorbed through buccal cavity, constitute critical drug delivery method. Spray drying, sublimation, other scientific procedures like freeze moulding, direct compression. . availability as over-the-counter drugs for treatment range illnesses increasing. This article's objective go over benefits, drawbacks, formulation difficulties, manufacturing methods, patented technologies, commercially available formulations, evaluation checks ODT. word "Oro dispersible tablets" was created by European Pharmacopoeia. an uncoated easily 3 minutes before being swallowed.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Formulation and taste masking of Ranitidine orally disintegrating tablet

Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

متن کامل

Formulation and taste masking of Ranitidine orally disintegrating tablet

Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

متن کامل

Formulation and Evaluation of a Novel Matrix-Type Orally Disintegrating Ibuprofen Tablet

Orally disintegrating tablets (ODTs) are capable of turning quickly into a liquid dosage form in contact with the saliva, thus possessing the advantages of both the solid dosage forms particularly stability and liquid dosage forms specially ease of swallowing and pre-gastric absorption of drug. The aim of this study was to prepare a novel matrix-type buccal fast disintegrating ibuprofen tablet ...

متن کامل

Design, Formulation, and Physicochemical Evaluation of Montelukast Orally Disintegrating Tablet

BACKGROUND Orally disintegrating tablets (ODTs) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. These tablets have advantages, particularly good applications for children and old patients who have a complication in chewing or swallowing solid dosage forms. The aim of this study was to design, formulate, and evaluate the physicochemical properties of 5 mg mon...

متن کامل

Formulation and Evaluation of a Novel Matrix-Type Orally Disintegrating Ibuprofen Tablet

Orally disintegrating tablets (ODTs) are capable of turning quickly into a liquid dosage form in contact with the saliva, thus possessing the advantages of both the solid dosage forms particularly stability and liquid dosage forms specially ease of swallowing and pre-gastric absorption of drug. The aim of this study was to prepare a novel matrix-type buccal fast disintegrating ibuprofen tablet ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: World Journal of Biology Pharmacy and Health Sciences

سال: 2022

ISSN: ['2582-5542']

DOI: https://doi.org/10.30574/wjbphs.2022.11.3.0124